substance

central, essential, mean, meaty, pithy, substantial, summate

capital, cognitive content, communication, component, component part, constituent, content, idea, matter, mental object, part, physical entity, portion, property, thought

acknowledgement, acknowledgment, activator, adulterant, adulterator, agent, allergen, antigen, approval, aside, assay, atom, bare bones, body, body substance, breakableness, bunk, carcinogen, chemical element, chemical irritant, chemistry, commendation, commitment, connotation, corker, counsel, counseling, counselling, dedication, denaturant, denotation, digestive, digression, direction, disapproval, discourtesy, disrespect, divagation, drivel, element, elixir, entry, essence, excursus, extension, ferment, fluid, fomentation, food, fuel, garbage, gaseousness, guidance, haecceity, hardness, hokum, humectant, humor, humour, hydrocolloid, hypostasis, implication, import, info, information, inhibitor, inoculant, inoculum, insertion, instruction, interpolation, jelly, latent content, leaven, leavening, ligand, living substance, lube, lubricant, lubricating substance, lubricator, lysin, material, meaning, meaninglessness, medium, memorial, metabolite, mixture, narration, narrative, nonsense, nonsensicality, nutrient, offer, offering, opinion, packaging, parenthesis, petition, philosopher's stone, philosophers' stone, phlogiston, pocketbook, poison, poisonous substance, porosity, porousness, postulation, promo, promotion, promotional material, propellant, propellent, proposal, protoplasm, publicity, pyrectic, pyrogen, quiddity, quintessence, reference, refrigerant, refusal, reminder, request, respects, semantics, sensationalism, shocker, significance, signification, softness, solidity, solidness, statement, story, strain, stuff, subject, submission, substrate, tale, tenor, theme, thickness, thinness, topic, toxicant, unbreakableness, undercurrent, undertone, vehicle, view, viscosity, viscousness, volatile, wherewithal, wit, witticism, wittiness